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It has fallen out of favor for that use because of the advent of digoxin antibody fragments.
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, digoxin, lithium, theophylline , in which elevated levels are often associated with serious medical complications and are, therefore, to be avoided.
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Verapamil, felodipine and tiapamil increase serum digoxin levels.
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6-10 ; however, morbidity is 50 if the digoxin level is greater than 6 ng ml.
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The serum concentration of digoxin should always be interpreted in the overall clinical context, and an isolated measurement should not be used alone as the basis for increasing or decreasing the dose of the drug.
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administration of cardizem with digoxin in 24 healthy male subjects increased plasma digoxin concentrations approximately 20 .
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